Cathie Wood doubles down on AI investments by boosting stakes in Nvidia and AMD, while reducing her Palantir holdings. This strategic shift highlights her confidence in the future of AI technology and precision medicine.

In a bold move that underscores her confidence in the burgeoning artificial intelligence (AI) sector, Cathie Wood, the renowned investor at the helm of Ark Invest, has once again reshuffled her portfolio.
This time, she has placed a significant wager on two of the most prominent players in the AI chip market, Nvidia and Advanced Micro Devices (AMD), while strategically trimming her position in Palantir Technologies.
On May 7, 2025, Ark Invest executed a series of trades that reflect its dynamic approach to navigating the fast-paced tech landscape.
The firm poured approximately $24 million into Nvidia and AMD, further solidifying its commitment to the AI revolution.
Nvidia, known for its leadership in AI and graphics processing, has been riding a wave of positive sentiment thanks to robust earnings from major tech players like Microsoft and Meta Platforms.
The company’s shares were snapped up across multiple Ark ETFs, including ARK Innovation, ARK Autonomous Technology & Robotics, ARK Next Generation Internet, and ARK Fintech Innovation.
The total acquisition amounted to 107,661 shares, valued at roughly $12.6 million.
Similarly, AMD has been gaining momentum, especially in the data center and AI chip markets, bolstered by a strategic investment from Amazon.
Ark Invest’s confidence in AMD’s trajectory was evident as it acquired a considerable number of shares across its various ETFs, amounting to 114,581 shares worth approximately $11.5 million.
While Wood’s enthusiasm for AI chips is palpable, her decision to offload $38.8 million worth of Palantir shares might raise a few eyebrows.
Despite Palantir’s strong first-quarter earnings, its stock has been under pressure, leading Ark to reduce its stake in the company across several ETFs.
This move follows a previous sale of $41 million in Palantir shares just a day earlier.
However, Palantir remains a significant part of Ark’s portfolio, making up 6.62% with a total value of $324.4 million, underscoring a calculated shift rather than a complete divestment.
Wood’s strategic play doesn’t stop at Nvidia and AMD.
In a nod to the promising potential of precision medicine, Ark Invest also acquired shares in Tempus AI, a company that recently reported impressive first-quarter results.
This acquisition, valued at $4.4 million, highlights Ark’s interest in investing in companies at the intersection of AI and healthcare, an area poised for exponential growth.
The decision to invest heavily in AI chip makers comes at a time when the demand for high-performance computing and AI capabilities is reaching unprecedented levels.
Nvidia and AMD are at the forefront of this technological revolution, providing the essential hardware that powers everything from cloud computing to autonomous vehicles.
As industries increasingly rely on AI for efficiency and innovation, the demand for sophisticated chips is expected to soar.
Cathie Wood’s investment philosophy has always been forward-thinking, often focusing on disruptive technologies with the potential to reshape industries.
Her latest moves are a testament to this vision, aligning Ark Invest with the forces driving the future of technology.
By betting on Nvidia and AMD, Wood is positioning her firm to capitalize on the AI wave, which shows no signs of slowing down.
However, Wood’s decision to pare down her Palantir holdings should not be seen as a lack of confidence in the company.
Instead, it reflects a strategic reallocation of resources, ensuring that Ark’s portfolio remains nimble and responsive to market conditions.
Palantir’s continued presence as a major holding signals that Wood still believes in its long-term prospects, even as she adjusts her short-term strategy.
As Ark Invest continues to maneuver through the complexities of the tech market, investors will undoubtedly keep a close eye on Wood’s moves.
Her ability to anticipate trends and adapt her portfolio accordingly has made her a prominent figure in the investment world.
With AI poised to drive the next wave of technological advancement, Wood’s latest trades are a clear indication of where she believes the future lies.
As always, her actions speak volumes, offering a glimpse into the evolving landscape of innovation and investment.